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Nolvadex (Tamoxifen)
TEVA$120.00
100-20mg Tabs
Nolvadex (Tamoxifen) belongs to a category and class of drugs known as selective Estrogen receptor modulators (SERMs). Selective Estrogen receptor modulators belong to an even broader class of drugs known as anti-estrogens. The other subcategory of drugs under the anti-estrogens category is known as aromatase inhibitors (AIs), such as Aromasin (Exemestane) and Arimidex (Anastrozole). AIs and SERMs make up anti-estrogens. Aromatase inhibitors differ greatly from SERMs in their action and how they deal with the issues of estrogen control. The misunderstanding that SERMs, such as Nolvadex and Clomid, serve to lower estrogen levels must first be addressed before delving into any further details.
Learn more about Nolvadex (Tamoxifen).
Nolvadex (Tamoxifen) Usage
Usage: 10-40 mg/day
Nolvadex (Tamoxifen) General Information
Nolvadex, also known as Tamoxifen, belongs to the sex hormone group of medications. While not an anabolic drug itself, Nolvadex is commonly utilized in bodybuilding for two main purposes:
Auxiliary Drug in Steroid Cycles:- Used to prevent the manifestation of adverse reactions during anabolic-androgenic steroid cycles.
- Helps counteract the increase in female sex hormones (estrogens) induced by androgenic-anabolic medications, reducing the risk of conditions such as gynecomastia (breast growth in males), obesity of the female type, and excessive water retention.
- Employed to restore the regular functioning of the human body after the completion of anabolic-androgenic steroid cycles.
Originally developed for medical purposes, particularly in the treatment of breast cancer, Nolvadex has found application in the realm of sports due to its ability to mitigate estrogen-related side effects caused by anabolic steroid usage. Signs of gynecomastia, such as pain, itching around the nipples, swelling, and potential discharge, can be indications that Nolvadex may be beneficial in preventing or addressing these issues.
Nolvadex (Tamoxifen) Benefits
Nolvadex is part of the group of non-steroid antiestrogens suppressing the receptors of estrogen. The primary activity of the drug includes restoring the concentration of the primary male sex hormone in the body while increasing the levels of estrogen. Athletes may use Nolvadex to remove excess fat deposits when on a low-calorie diet, increase muscle mass development and stop the already observable adverse reactions associated with steroids.
The key effects of using the drug encompass:
Restoration of Endogenous Testosterone Production:- Nolvadex helps stimulate the production of endogenous testosterone, aiding in the recovery of natural hormone levels.
- By inhibiting estrogen activity throughout the body, including the hypothalamus and pituitary gland, Nolvadex not only facilitates the restoration of male hormone development but also prevents fluid retention, swelling, and minimizes setbacks associated with excess estrogen.
- The drug contributes to a higher concentration of high-density cholesterol in the bloodstream, promoting a favorable ratio of "good" cholesterol to "bad" cholesterol. This reduction in the risk of cardiovascular diseases is particularly beneficial for competitive athletes.
Nolvadex is generally well-tolerated, with its primary impact on estrogen concentration occurring in the liver cells. This characteristic is advantageous for the body. Research indicates that a daily dose of 20 mg for ten consecutive days can increase testosterone concentration by 42% compared to endogenous levels. With a usage period extending beyond 1.5 months, the elevation in the main male hormone level reaches 83%.
Nolvadex (Tamoxifen) Possible Side Effects
Despite its efficacy, Nolvadex may lead to several side effects, largely attributable to its antiestrogenic properties. Women who fail to adhere to prescribed dosages and usage durations may experience adverse effects, including partial or complete hair loss, hot flashes, genital itching, and bone pain.
Male athletes may encounter side effects such as increased body temperature, nausea, dizziness, and compromised kidney function due to fluid retention. Other potential issues include severe headaches, anxiety, somnolence, digestive disorders like constipation or anorexia, and fatigue. Eye-related side effects may include swelling, cataracts, partial or total vision loss. Skin rash, migraines, changes in the cornea, and confusion have also been reported. Individuals with serious liver diseases, such as hepatitis, are cautioned against using Nolvadex, as it can exacerbate damage to the liver.
The antiestrogenic properties of Nolvadex increase progesterone receptors. Therefore, if an anabolic cycle involves progesterone medications like trenbolone and nandrolone, Nolvadex is not recommended during the cycle or post-cycle therapy (PCT). Using trenbolone and nandrolone after Nolvadex can lead to prolactin-induced gynecomastia.
In case of side effects, it is advisable to discontinue Nolvadex immediately and substitute it with another antiestrogen, such as Clomid or Toremifene. Toremifene, being a modified version of Nolvadex, is suggested as an alternative with fewer adverse reactions.
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