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Ibutamoren (MK-677)
Peak Pharma$60.00
60 Tablets
MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release from the brain.
Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition. Therefore, we can expect that ibutamoren may also affect these functions. It increases growth hormone levels with little or no increase in other hormones, such as cortisol.
Learn more about Ibutamoren (MK-677).
Ibutamoren (MK-677) Usage
Usage: 20-30 mg/day
Cycle Duration: 8-12 weeks
Ibutamoren (MK-677) Benefits
Ibutamoren, often used by athletes to enhance muscle volume, strength, endurance, and fat reduction, offers several positive properties. Ibutamoren's benefits include stimulating the production of natural somatotropin (growth hormone) and insulin-like growth factor 1. It helps build lean muscle mass, improve strength performance, enhance bone tissue strength, boost endurance, stimulate fat burning, accelerate metabolism, strengthen the immune system, improve sleep, hasten healing processes, and aid in the restoration of injured ligaments and tendons, among other benefits.
Scientific testing has shown that a single administration of Ibutamoren at a dosage of 25 mg results in an average peak concentration of somatotropin equal to 22.1 mcg/l. Larger doses can lead to even higher concentrations. The drug maintains a steady concentration of growth hormone in plasma, allowing for even production.
Regular use of MK-677 increases the concentration of insulin-like growth factor 1 by 39-89% of initial values. MK-677 impacts various brain regions responsible for metabolic processes by reducing somatostatin concentration (a peptide hormone that suppresses growth hormone production), increasing GHRH hormone production (stimulates growth hormone production), assisting signals in the pituitary GHRH hormone, and blocking signals of somatostatin receptors.
By elevating somatotropin concentration, Ibutamoren enhances muscle volume, strength, and reduces body fat. It has been shown to decrease muscle loss, enhance muscle strength and walking speed (especially noticeable in older individuals), and increase bone mineralization. Studies indicate that Ibutamoren also improves the duration and quality of sleep. Importantly, the drug lacks androgenic effects, making it safe for female athletes to use without the risk of developing secondary male sexual characteristics.
Ibutamoren (MK-677) Possible Side Effects
The active ingredient in Ibutamoren typically does not cause adverse reactions. Some athletes may experience numbness in the upper limbs and fingers, feelings of fatigue, and a slight increase in appetite. These reactions are indicative of an elevated concentration of somatotropin, highlighting the effectiveness of the drug. However, it's worth noting that not all users may experience these symptoms.
Similar to the action of growth hormone, Ibutamoren can lead to fluid retention in the body. This issue can be addressed by making adjustments to the diet or, if necessary, by using diuretics. It's important for individuals using the drug to monitor their responses and make any necessary adjustments to mitigate potential side effects.
Ibutamoren (MK-677) Other Information
The effectiveness of using Ibutamoren is not dependent on age, gender, or other physical characteristics of the user. The recommended daily dosage is 25 mg, which is comparable to the injection of recombinant somatotropin. For athletes weighing up to 80 kg, one capsule (containing 25 mg of the drug) should be taken once a day at bedtime on an empty stomach. If evening use interferes with sleep, the capsule can be consumed in the morning on an empty stomach before eating. MK-677 may cause drowsiness, so taking the capsule before bedtime is advisable.
For athletes weighing more than 80 kg, the recommended dosage is 2 capsules per day – one in the morning before a meal on an empty stomach and one at bedtime. The activation of somatotropin production after a single use of the drug lasts for 8 hours or more, effectively enhancing the secretion of IGF-1. It's important for users to follow these guidelines to optimize the benefits of Ibutamoren.
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