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Aromasin (Exemestane)

Aromasin (Exemestane)

Peak Pharma
50 Tablets
Aromasin protects against estrogen-related side effects. It is a mild Aromatase Inhibitor used to prevent gyno during highly androgenic steroid cycles.

Learn more about Aromasin (Exemestane).

Aromasin (Exemestane) Usage

Usage: 12.5-25 mg/day

Aromasin (Exemestane) General Information

Aromasin (Exemestane) is a potent antiestrogen medication widely utilized in bodybuilding and other power sports to address negative side effects associated with estrogen, particularly those induced by the use of potent androgenic and anabolic steroids.

The drug is employed during steroid cycles to manage issues such as gynecomastia, high blood pressure, excessive water retention, female pattern fat deposits, reduced libido, and low sexual activity. It is also commonly used in post-cycle therapy to reduce estradiol levels after the completion of a steroid cycle.

Initially developed for medicinal purposes, Aromasin, like many other antiestrogen drugs, was primarily intended for treating estrogen-related cancers. However, it has gained popularity among athletes and is considered relatively safe for human use when proper dosages are adhered to. Aromasin is produced in tablet form, with each tablet containing 25 mg of the active agent. The safety and efficacy of exemestane have been affirmed through laboratory and clinical testing, leading to its FDA approval. Nevertheless, its use is strictly controlled in sports due to the classification of many aromatase inhibitors as performance-enhancing substances.

Exemestane is the active agent in Aromasin, classified as an antiestrogen due to its pharmacological class and action. It belongs to the third generation of aromatase inhibitors and was originally formulated for medicinal use. Initially available as a white crystalline powder soluble in alcohol but not in water, it is now primarily administered in tablet form.

Aromasin's mechanism of action is comparable to other antiestrogens such as Letrozole or Anastrozole. It irreversibly inhibits aromatase enzymes by binding with the active aromatase center, leading to the suppressed production of female sex hormones (estrogens). Unlike many other antiestrogens, Aromasin is of steroidal origin, allowing it to produce slight androgenic activity without progestogenic or estrogenic effects.

While Aromasin can stimulate testosterone production by increasing the number of hormones that stimulate testosterone, it is less effective than dedicated testosterone boosters. The primary effect of the drug is antiestrogenic, resulting in a significant decrease (60-80% of the initial concentration) in the levels of estrone, estradiol, and estrone sulfate in the bloodstream. Importantly, the aromatase inhibitor does not impact the synthesis of cortisol, aldosterone production in the adrenal glands, or thyroxine secretion in the thyroid gland.

Aromasin (Exemestane) Benefits

Aromasin facilitates significant reductions in estrogen concentration in the bloodstream, leading to a more stable endocrine profile without spikes during or after a steroid cycle. Bodybuilders commonly use Aromasin due to the following positive effects:

  • Reduced Concentration of Estrogens by 60-80%: Aromasin helps decrease estrogen levels substantially, contributing to hormonal balance.
  • Increased Amount of Anabolic Hormones: The drug supports an increase in anabolic hormones, fostering a favorable environment for muscle growth.
  • Prevention of Gynecomastia: Aromasin aids in preventing the development of gynecomastia, a condition characterized by the enlargement of male breast tissue.
  • Improved Excretion of Excess Fluid: The medication assists in the efficient excretion of excess fluid, reducing bloating and enhancing muscle definition.
  • Enhanced Body Definition: Aromasin contributes to improved body definition, helping athletes achieve a more sculpted physique.
  • Normalization of the Hypothalamic–Pituitary–Gonadal Axis Function: The drug supports the normalization of the hypothalamic–pituitary–gonadal axis, crucial for hormonal balance.
  • Restoration of Normal Blood Pressure: Aromasin aids in restoring normal blood pressure, mitigating one of the potential adverse effects of steroid use.

The maximal concentration of the active component of Aromasin is achieved within 2 hours after a single intake, allowing for a rapid onset of the drug's beneficial effects. The aromatase inhibitor is completely eliminated from the body within a week after ingestion.

Aromasin (Exemestane) Possible Side Effects

Aromasin can be used by both experienced athletes and beginners, but exceeding the prescribed dosages can result in the suspension of muscle growth and may cause side effects such as depression, insomnia, nausea, reduced libido, excessive sweating, acne, and reduced bone density, as well as joint pain. These effects typically subside quickly after reducing the dosage or discontinuing the drug.

Despite its effectiveness, Exos by Pharmacom Labs is prohibited for use by the elderly and athletes with kidney diseases, myocardial infarction, and other heart conditions. Additionally, individuals with oversensitivity to the active agent should avoid its use.

Aromasin (Exemestane) Other Information

Aromasin can be utilized in both traditional medicine and sports pharmacology. The recommended daily dosage ranges between 12.5-25 mg, which is sufficient for suppressing gynecomastia and reducing estrogen production. It is advised not to exceed the optimal dosage, as doing so may increase the risks of negative side effects without additional benefits.

The drug is rapidly absorbed into the bloodstream, and experts suggest taking it after food intake to enhance tablet absorption (by +40%). There are two main methods for Aromasin intake:

  • Preventive Usage: Minimal dosage of 12.5 mg every other day starting from the first week throughout the entire drug cycle to prevent adverse side effects.
  • Symptomatic Usage: The drug can be incorporated into a cycle if symptoms of gynecomastia or other side effects manifest at the beginning, middle, or end of the steroid cycle. In this case, the dosage is 25 mg daily until all symptoms are suppressed, followed by a reduced dosage of 12.5 mg every other day.

Aromasin is recommended during particularly heavy steroid cycles that pose a higher risk of side effects associated with estrogen. The drug is not deemed necessary during milder drug cycles or when using anabolic androgenic steroids that do not aromatize.

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